Discovery of an Evolutionary Synergy for Stress Acclimation in Plants
Publication from the NUTS team in a collaboration, in Science Advances, June 2024
The discovery of a new mechanism that allows plants to optimize their photosynthesis is unveiled in the pages of the journal Science Advances. Interestingly, this mechanism involves molecules of bacterial origin, opening up promising prospects for the development of agriculture that is more resilient to climate change.
> More, news from The "Cité des énergie", CEA
Abstract
Posttranslational regulation of photosynthetic activity via the TOR kinase in plants
Chloroplasts are the powerhouse of the plant cell, and their activity must be matched to plant growth to avoid photooxidative damage Researchers, in an international collaboration that incuded members of the "Nitrogen Use, transport and signaling" NUTS team and the IJPB plateform "The Plant Observatory - Chemistry/Metabolism" PO-Chem have identified a posttranslational mechanism linking the eukaryotic target of rapamycin (TOR) kinase that promotes growth and the guanosine tetraphosphate (ppGpp) signaling pathway of prokaryotic origins that regulates chloroplast activity and photosynthesis in particular. They discovered that the RelA SpoT homolog 3 (RSH3), a nuclear-encoded enzyme responsible for ppGpp biosynthesis, interacts directly with the TOR complex via a plant-specific amino-terminal region which is phosphorylated in a TOR-dependent manner. Down-regulating TOR activity causes a rapid increase in ppGpp synthesis in RSH3 overexpressors and reduces photosynthetic capacity in an RSH-dependent manner in wild-type plants. The TOR-RSH3 signaling axis
* Collaboration :
> Aix Marseille Univ, CEA, CNRS, BIAM, équipe LGBP, Marseille, France
> Aix Marseille Univ, CNRS, Plate-forme Protéomique, Marseille Protéomique (MaP), Marseille, France
> Institut Jean-Pierre Bourgin - Sciences de Végétal IJPB, Université Paris-Saclay, INRAE, AgroParisTech, Versailles, France
> Università di Torino, Department of Life Sciences and Systems Biology, Torino, Italy
> University of Tunis El Manar, Faculté des Sciences de Tunis, Tunisia
Research developed at the Institute Jean-Pierre Bourgin for Plant Sciencess in collaboration.
> More, news from The "Cité des énergie", CEA
Abstract
Posttranslational regulation of photosynthetic activity via the TOR kinase in plants
Chloroplasts are the powerhouse of the plant cell, and their activity must be matched to plant growth to avoid photooxidative damage Researchers, in an international collaboration that incuded members of the "Nitrogen Use, transport and signaling" NUTS team and the IJPB plateform "The Plant Observatory - Chemistry/Metabolism" PO-Chem have identified a posttranslational mechanism linking the eukaryotic target of rapamycin (TOR) kinase that promotes growth and the guanosine tetraphosphate (ppGpp) signaling pathway of prokaryotic origins that regulates chloroplast activity and photosynthesis in particular. They discovered that the RelA SpoT homolog 3 (RSH3), a nuclear-encoded enzyme responsible for ppGpp biosynthesis, interacts directly with the TOR complex via a plant-specific amino-terminal region which is phosphorylated in a TOR-dependent manner. Down-regulating TOR activity causes a rapid increase in ppGpp synthesis in RSH3 overexpressors and reduces photosynthetic capacity in an RSH-dependent manner in wild-type plants. The TOR-RSH3 signaling axis
* Collaboration :
> Aix Marseille Univ, CEA, CNRS, BIAM, équipe LGBP, Marseille, France
> Aix Marseille Univ, CNRS, Plate-forme Protéomique, Marseille Protéomique (MaP), Marseille, France
> Institut Jean-Pierre Bourgin - Sciences de Végétal IJPB, Université Paris-Saclay, INRAE, AgroParisTech, Versailles, France
> Università di Torino, Department of Life Sciences and Systems Biology, Torino, Italy
> University of Tunis El Manar, Faculté des Sciences de Tunis, Tunisia
Research developed at the Institute Jean-Pierre Bourgin for Plant Sciencess in collaboration.
Back
Légend: WT and a mutant of the TOR complex
Référence
S D’Alessandro, F Velay, Régine Lebrun, D Zafirov, M Mehrez, S Romand, R Saadouni, C Forzani, S Citerne, MH Montané, C Robaglia, B Menand, C Meyer and B Field. (2024). Posttranslational regulation of photosynthetic activity via the TOR kinase in plants. Science Advances, https://www.science.org/doi/10.1126/sciadv.adj3268
Contact IJPB
Christian Meyer, contact, "Nitrogen Use, transport and signaling" NUTS team