Clément Pichot INRAE research scientist joins the BCR team
Topic: study of androgenesis induction
Clément Pichot, a new member of the "Cell Biology and Plant Regeneration" BCR team, will be carrying out the following research project:
Plant androgenesis allows haploid male gametes to be reprogrammed towards embryogenic development and, eventually, the production of doubled haploid plants to accelerate plant breeding. However, some cereals - in particular certain wheat or barley accessions - remains strongly recalcitrant to regeneration via androgenesis. My project aims to understand the early mechanisms that control the initiation of androgenesis in monocots, using Brachypodium distachyon as a model and bread wheat as the target species. Its asssumption is that key molecular and epigenetic factors associated with embryogenic competence, especially those acting transiently, may be tuned to enhance the production of doubled haploid plants in recalcitrant genotypes. The project relies initially on the integrative analysis of multi-omic temporal datasets combining gene expression, chromatin accessibility, DNA methylation, histone marks, and 3D genome organization, based on sorted- and single-cell approaches. Results first obtained in Brachypodium will serve as starting points for a translational biology strategy applied to bread wheat.
Clément Pichot, Mini-CV :
2026 - today : Research Scientist INRAE, IJPB
2024 - 2026 : Post-Doc, INRAE, IJPB, "Cell Biology and Plant Regeneration" BCR team - Characterization of the factors regulating induced somatic embryogenesis in Brachypodium distachyon
2022-2024 : Chief Technical Officer (CTO), start-up Genomines,"Institute of Plant Sciences Paris-Saclay" IPS2, Gif-sur-Yvette
Gif-sur-Yvette,
2018-2022 : Doctorat, Institute of Plant Sciences Paris-Saclay IPS2, Gif-sur-Yvette, Université Paris-Saclay - IIdentification and characterization of cis- and trans-regulatory elements of the genes controlling sex determination in Cucumis melo. Directeur de thèse : Abdelhafid Bendahmane
Plant androgenesis allows haploid male gametes to be reprogrammed towards embryogenic development and, eventually, the production of doubled haploid plants to accelerate plant breeding. However, some cereals - in particular certain wheat or barley accessions - remains strongly recalcitrant to regeneration via androgenesis. My project aims to understand the early mechanisms that control the initiation of androgenesis in monocots, using Brachypodium distachyon as a model and bread wheat as the target species. Its asssumption is that key molecular and epigenetic factors associated with embryogenic competence, especially those acting transiently, may be tuned to enhance the production of doubled haploid plants in recalcitrant genotypes. The project relies initially on the integrative analysis of multi-omic temporal datasets combining gene expression, chromatin accessibility, DNA methylation, histone marks, and 3D genome organization, based on sorted- and single-cell approaches. Results first obtained in Brachypodium will serve as starting points for a translational biology strategy applied to bread wheat.
Clément Pichot, Mini-CV :
2026 - today : Research Scientist INRAE, IJPB
2024 - 2026 : Post-Doc, INRAE, IJPB, "Cell Biology and Plant Regeneration" BCR team - Characterization of the factors regulating induced somatic embryogenesis in Brachypodium distachyon
2022-2024 : Chief Technical Officer (CTO), start-up Genomines,"Institute of Plant Sciences Paris-Saclay" IPS2, Gif-sur-Yvette
Gif-sur-Yvette,
2018-2022 : Doctorat, Institute of Plant Sciences Paris-Saclay IPS2, Gif-sur-Yvette, Université Paris-Saclay - IIdentification and characterization of cis- and trans-regulatory elements of the genes controlling sex determination in Cucumis melo. Directeur de thèse : Abdelhafid Bendahmane
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