Corinne MHIRI Research Engineer

Epigenetics, Reproduction and Transposable Elements

I am interested in the impact of transposable elements on Nicotiana genome dynamics following different stress, such as interspecific hybridizations
I belong to the RETROS team directed by Marie-Angèle Grandbastien since 2002.


- Study of transposable element (TE) impact on Nicotiana genome structure and expression.

- In charge of a SSAP (Sequence-Specific Amplification Polymorphism) technical platform to detect transposable elements (TEs) insertion profiles

- Developing bioinformatic analysis to annotate and evaluate the expression level of TEs

- Radiation safety management at IJPB : providing technical support as a radiation safety officer to IJPB radioactivity users

- Student research training (undergraduated to graduated students)  

Education & courses  

- 1992 : Agronomy Engineer (Master in Plant Pathology), Institut National Agronomique –Paris-Grignon (INA-PG / AgroParisTech), Paris « Study of the BNYVV P42 protein in the virus cell-to-cell diffusion mechanisms by immunocytochemistry" - INRA Colmar  

- 1996 : PhD in Plant Pathology, INA-PG /AgroParisTech, Paris « Activation of the Tnt1 retrotransposon following stress and phytopathogen attacks" - INRA Versailles (Biologie Cellulaire laboratory / IJPB)

- 2005 : Radiation Safety Officer Certificate (updates in 2010, 2015 and 2019)

- 2020 : Preparing a Bioinformatic Certificate delivered by the University of Paris and the French Bioinformatic Institute
Synthetic Nicotiana hybrid collection maintained by in vitro culture
Example of SSAP gel allowing the vizualisation of transposable element insertion changes (the different plants are in columns, each line corresponds to a specific insertion locus) Synthetic tobaccos in greenhouse condition From right to left : 4 synthetic tobacco hybrid flowers and their two parents, Nicotiana sylvestris and N. tomentosiformis