Chowdhury NB, Simons-Senftle M, Decouard B, Quilleré I, Rigault M, Sajeevan KA, Acharya B, Chowdhury R, Hirel B, Dellagi A, Maranas CD, Saha R (2023). A multi-organ maize metabolic model connects temperature stress with energy production and reducing power generation. iScience, 26(12):108400. PubMed | DOI

Terce Laforgue T, Lothier J, Limami AM, Rouster J, Lea PJ, Hirel B (2023). The Key Role of Glutamate Dehydrogenase 2 (GDH2) in the Control of Kernel Production in Maize (Zea mays L.). Plants, 12(14):2612. PubMed | DOI

Limami AM, Cukier C, Hirel B (2023). 15N-labelling of Leaves Combined with GC-MS Analysis as a Tool for Monitoring the Dynamics of Nitrogen Incorporation into Amino Acids. Methods Mol Biol, 2642:151-161. PubMed | DOI

Mazoyon C, Hirel B, Pecourt A, Catterou M, Gutierrez L, Sarazin A, Dubois F, Duclercq J (2023). Sphingomonas sediminicola Is an Endosymbiotic Bacterium Able to Induce the Formation of Root Nodules in Pea (Pisum sativum L.) and to Enhance Plant Biomass Production. Microorganisms, 11(1):199. PubMed | DOI

Limami A, Hirel B, Lothier J (2022). Does Potassium (K+) Contribute to High-Nitrate (NO3-) Weakening of a Plant's Defense System against Necrotrophic Fungi?. Int J Mol Sci, 23(24):15631. PubMed | DOI

Chowdhury NB, Schroeder WL, Sarkar D, Amiour N, Quilleré I, Hirel B, Maranas CD, Saha R (2022). Dissecting the metabolic reprogramming of maize root under nitrogen-deficient stress conditions. J Exp Bot, 73(1):275-291. PubMed | DOI

Valderrama-Martín JM, Ortigosa F, Ávila C, Cánovas FM, Hirel B, Cantón FR, Cañas RA (2022). A revised view on the evolution of glutamine synthetase isoenzymes in plants. Plant J. PubMed | DOI

Amiour N, Décousset L, Rouster J, Quenard N, Buet C, Dubreuil P, Quilleré I, Brulé L, Cukier C, Dinant S, Sallaud C, Dubois F, Limami AM, Lea PJ, Hirel B (2021). Impacts of environmental conditions, and allelic variation of cytosolic glutamine synthetase on maize hybrid kernel production. Commun Biol, 4(1):1095. PubMed | DOI

Cañas RA, Yesbergenova-Cuny Z, Belanger L, Rouster J, Brulé L, Gilard F, Quilleré I, Sallaud C, Hirel B (2020). NADH-GOGAT Overexpression Does Not Improve Maize (Zea mays L.) Performance Even When Pyramiding with NAD-IDH, GDH and GS. Plants, 9:. PubMed | DOI

Dellagi A, Quilleré I, Hirel B (2020). Beneficial soil-borne bacteria and fungi: a promising way to improve plant nitrogen acquisition. J Exp Bot, . PubMed | DOI

Cukier C, Lea PJ, Canas R, Marmagne A, Limami AM, Hirel B (2018). Labeling Maize (Zea mays L.) Leaves with (15) NH4(+) and Monitoring Nitrogen Incorporation into Amino Acids by GC/MS Analysis. Curr Protoc Plant Biol, 3:e20073. PubMed | DOI

Quilleré I, Dargel-Graffin C, Lea PJ, Hirel B (2018). Variability for Nitrogen Management in Genetically-Distant Maize (Zea mays L.) Lines: Impact of Post-Silking Nitrogen Limiting Conditions. Agronomy, 8:. PubMed | DOI

Brusamarello-Santos LC, Gilard F, Brulé L, Quilleré I, Gourion B, Ratet P, Maltempi De Souza E, Lea PJ, Hirel B (2017). Metabolic profiling of two maize (Zea mays L.) inbred lines inoculated with the nitrogen fixing plant-interacting bacteria Herbaspirillum seropedicae and Azospirillum brasilense. PLoS One, 12:e0174576. PubMed | DOI

Cañas RA, Yesbergenova-Cuny Z, Simons M, Chardon F, Armengaud P, Quilleré I, Cukier C, Gibon Y, Limami AM, Nicolas S, Brulé L, Lea PJ, Maranas CD, Hirel B (2017). Exploiting the Genetic Diversity of Maize Using a Combined Metabolomic, Enzyme Activity Profiling, and Metabolic Modeling Approach to Link Leaf Physiology to Kernel Yield. Plant Cell, 29:919-943. PubMed | DOI

Habbib H, Hirel B, Verzeaux J, Roger D, Lacoux J, Lea P, Dubois F, Tétu T (2017). Investigating the Combined Effect of Tillage, Nitrogen Fertilization and Cover Crops on Nitrogen Use Efficiency in Winter Wheat. Agronomy, 7:66. PubMed | DOI

Verzeaux J, Hirel B, Dubois F, Lea PJ, Tétu T (2017). Agricultural practices to improve nitrogen use efficiency through the use of arbuscular mycorrhizae: Basic and agronomic aspects. Plant Sci, 264:48-56. PubMed | DOI

Verzeaux J, Nivelle E, Roger D, Hirel B, Dubois F, Tétu T (2017). Spore Density of Arbuscular Mycorrhizal Fungi is Fostered by Six Years of a No-Till System and is Correlated with Environmental Parameters in a Silty Loam Soil. Agronomy, 7:38. PubMed | DOI

Cormier F, Foulkes J, Hirel B, Gouache D, Moënne-Loccoz Y, Le Gouis J, Ordon F (2016). Breeding for increased nitrogen-use efficiency: a review for wheat (T. aestivumL.). Plant Breeding, 135:255-278. PubMed | DOI

Habbib H, Verzeaux J, Nivelle E, Roger D, Lacoux J, Catterou M, Hirel B, Dubois F, Tétu T (2016). Conversion to No-Till Improves Maize Nitrogen Use Efficiency in a Continuous Cover Cropping System. PLoS One, 11:e0164234. PubMed | DOI

Hirel B, Krapp A (2016). Special Issue: Nitrogen Transport and Assimilation in Plants. Agronomy, 6:41. PubMed | DOI

Verzeaux J, Alahmad A, Habbib H, Nivelle E, Roger D, Lacoux J, Decocq G, Hirel B, Catterou M, Spicher F, Dubois F, Duclercq J, Tétu T (2016). Cover crops prevent the deleterious effect of nitrogen fertilisation on bacterial diversity by maintaining the carbon content of ploughed soil. Geoderma, 281:49-57. PubMed | DOI

Verzeaux J, Roger D, Lacoux J, Nivelle E, Adam C, Habbib H, Hirel B, Dubois F, Tétu T (2016). In Winter Wheat, No-Till Increases Mycorrhizal Colonization thus Reducing the Need for Nitrogen Fertilization. Agronomy, 6:38. PubMed | DOI

Yesbergenova-Cuny Z, Dinant S, Martin-Magniette ML, Quilleré I, Armengaud P, Monfalet P, Lea PJ, Hirel B (2016). Genetic variability of the phloem sap metabolite content of maize (Zea mays L.) during the kernel-filling period. Plant Sci, 252:347-357. PubMed | DOI

Terce-Laforgue T, Clément G, Marchi L, Restivo FM, Lea PJ, Hirel B (2015). Resolving the Role of Plant NAD-Glutamate Dehydrogenase: III. Overexpressing Individually or Simultaneously the Two Enzyme Subunits Under Salt Stress Induces Changes in the Leaf Metabolic Profile and Increases Plant Biomass Production. Plant Cell Physiol, 56:1918-1929. PubMed | DOI

Amiour N, Imbaud S, Clément G, Agier N, Zivy M, Valot B, Balliau T, Quilleré I, Terce-Laforgue T, Dargel-Graffin C, Hirel B (2014). An integrated "omics" approach to the characterization of maize (Zea mays L.) mutants deficient in the expression of two genes encoding cytosolic glutamine synthetase. BMC Genomics, 15:1005. PubMed | DOI

Simons M, Saha R, Amiour N, Kumar A, Guillard L, Clément G, Miquel M, Li Z, Mouille G, Lea PJ, Hirel B, Maranas CD (2014). Assessing the metabolic impact of nitrogen availability using a compartmentalized maize leaf genome-scale model. Plant Physiol, 166:1659-1674. PubMed | DOI

Simons M, Saha R, Guillard L, Clément G, Armengaud P, Canas R, Maranas CD, Lea PJ, Hirel B (2014). Nitrogen-use efficiency in maize (Zea mays L.): from 'omics' studies to metabolic modelling. J Exp Bot, 65:5657-5671. PubMed | DOI

Fontaine JX, Terce-Laforgue T, Bouton S, Pageau K, Lea PJ, Dubois F, Hirel B (2013). Further insights into the isoenzyme composition and activity of glutamate dehydrogenase in Arabidopsis thaliana. Plant Signal Behav, 8:e23329. PubMed | DOI

Marchi L, Degola F, Polverini E, Terce-Laforgue T, Dubois F, Hirel B, Restivo FM (2013). Glutamate dehydrogenase isoenzyme 3 (GDH3) of Arabidopsis thaliana is regulated by a combined effect of nitrogen and cytokinin. Plant Physiol Biochem, 73:368-374. PubMed | DOI

Terce-Laforgue T, Bedu M, Dargel-Graffin C, Dubois F, Gibon Y, Restivo FM, Hirel B (2013). Resolving the role of plant glutamate dehydrogenase: II. Physiological characterization of plants overexpressing the two enzyme subunits individually or simultaneously. Plant Cell Physiol, 54:1635-1647. PubMed | DOI

Amiour N, Imbaud S, Clément G, Agier N, Zivy M, Valot B, Balliau T, Armengaud P, Quilleré I, Canas R, Tercet-Laforgue T, Hirel B (2012). The use of metabolomics integrated with transcriptomic and proteomic studies for identifying key steps involved in the control of nitrogen metabolism in crops such as maize. J Exp Bot, 63:5017-5033. PubMed | DOI

Cañas RA, Quilleré I, Gallais A, Hirel B (2012). Can genetic variability for nitrogen metabolism in the developing ear of maize be exploited to improve yield?. New Phytol, 194:440-452. PubMed | DOI

Fontaine JX, Terce-Laforgue T, Armengaud P, Clément G, Renou JP, Pelletier S, Catterou M, Azzopardi M, Gibon Y, Lea PJ, Hirel B, Dubois F (2012). Characterization of a NADH-dependent glutamate dehydrogenase mutant of Arabidopsis demonstrates the key role of this enzyme in root carbon and nitrogen metabolism. Plant Cell, 24:4044-4065. PubMed | DOI

Cañas RA, Amiour N, Quilleré I, Hirel B (2011). An integrated statistical analysis of the genetic variability of nitrogen metabolism in the ear of three maize inbred lines (Zea mays L.). J Exp Bot, 62:2309-2318. PubMed | DOI

Hirel B, Tétu T, Lea PJ, Dubois F (2011). Improving Nitrogen Use Efficiency in Crops for Sustainable Agriculture. Sustainability, 3:1452-1485. PubMed | DOI

Broyart C, Fontaine JX, Molinie R, Cailleu D, Terce-Laforgue T, Dubois F, Hirel B, Mesnard F (2010). Metabolic profiling of maize mutants deficient for two glutamine synthetase isoenzymes using 1H-NMR-based metabolomics. Phytochem Anal, 21:102-109. PubMed | DOI

Cañas RA, Quilleré I, Lea PJ, Hirel B (2010). Analysis of amino acid metabolism in the ear of maize mutants deficient in two cytosolic glutamine synthetase isoenzymes highlights the importance of asparagine for nitrogen translocation within sink organs. Plant Biotechnol J, 8:966-978. PubMed | DOI

Fontaine JX, Molinie R, Terce-Laforgue T, Cailleu D, Hirel B, Dubois F, Mesnard F (2010). Use of 1H-NMR metabolomics to precise the function of the third glutamate dehydrogenase gene in Arabidopsis thaliana. Comptes Rendus Chimie, 13:453-458. PubMed | DOI

Cañas RA, Quilleré I, Christ A, Hirel B (2009). Nitrogen metabolism in the developing ear of maize (Zea mays): analysis of two lines contrasting in their mode of nitrogen management. New Phytol, 184:340-352. PubMed | DOI

Fontaine JX, Ravel C, Pageau K, Heumez E, Dubois F, Hirel B, Le Gouis J (2009). A quantitative genetic study for elucidating the contribution of glutamine synthetase, glutamate dehydrogenase and other nitrogen-related physiological traits to the agronomic performance of common wheat. Theor Appl Genet, 119:645-662. PubMed | DOI

Labboun S, Terce-Laforgue T, Roscher A, Bedu M, Restivo FM, Velanis CN, Skopelitis DS, Moschou PN, Roubelakis-Angelakis KA, Suzuki A, Hirel B (2009). Resolving the role of plant glutamate dehydrogenase. I. In vivo real time nuclear magnetic resonance spectroscopy experiments. Plant Cell Physiol, 50:1761-1773. PubMed | DOI

Bernard SM, Moller AL, Dionisio G, Kichey T, Jahn TP, Dubois F, Baudo M, Lopes MS, Terce-Laforgue T, Foyer CH, Parry MA, Forde BG, Araus JL, Hirel B, Schjoerring JK, Habash DZ (2008). Gene expression, cellular localisation and function of glutamine synthetase isozymes in wheat (Triticum aestivum L.). Plant Mol Biol, 67:89-105. PubMed | DOI

Coque M, Martin A, Veyrieras JB, Hirel B, Gallais A (2008). Genetic variation for N-remobilization and postsilking N-uptake in a set of maize recombinant inbred lines. 3. QTL detection and coincidences. Theor Appl Genet, 117:729-747. PubMed | DOI

Gallais A, Coque M, Le Gouis J, Prioul JL, Hirel B, Quilleré I (2007). Estimating the Proportion of Nitrogen Remobilization and of Postsilking Nitrogen Uptake Allocated to Maize Kernels by Nitrogen-15 Labeling. Crop Sci, 47:685. PubMed | DOI

Hirel B, Chardon F, Durand J (2007). The contribution of molecular physiology to the improvement of nitrogen use efficiency in crops. J Crop Sci Biotech, 10:123-132. PubMed | DOI

Hirel B, Le Gouis J, Ney B, Gallais A (2007). The challenge of improving nitrogen use efficiency in crop plants: towards a more central role for genetic variability and quantitative genetics within integrated approaches. J Exp Bot, 58:2369-2387. PubMed | DOI

Kichey T, Hirel B, Heumez E, Dubois F, Le Gouis J (2007). In winter wheat (Triticum aestivum L.), post-anthesis nitrogen uptake and remobilisation to the grain correlates with agronomic traits and nitrogen physiological markers. Field Crops Research, 102:22-32. PubMed | DOI

Coque M, Bertin P, Hirel B, Gallais A (2006). Genetic variation and QTLs for 15N natural abundance in a set of maize recombinant inbred lines. Field Crops Research, 97:310-321. PubMed | DOI

Fei H, Chaillou S, Hirel B, Polowick P, Mahon JD, Vessey JK (2006). Effects of the overexpression of a soybean cytosolic glutamine synthetase gene (GS15) linked to organ-specific promoters on growth and nitrogen accumulation of pea plants supplied with ammonium. Plant Physiol Biochem, 44:543-550. PubMed | DOI

Fontaine JX, Saladino F, Agrimonti C, Bedu M, Terce-Laforgue T, Tétu T, Hirel B, Restivo FM, Dubois F (2006). Control of the synthesis and subcellular targeting of the two GDH genes products in leaves and stems of Nicotiana plumbaginifolia and Arabidopsis thaliana. Plant Cell Physiol, 47:410-418. PubMed | DOI