The PO-Chemistry/Metabolism platform is dedicated to the quantification of hormones and signaling molecules, characterisation of plant chemical compounds, primary and specialised metabolites and plant biomass. The PO-Chemistry/Metabolism provides this service to the international community.
Biological Question
The development of functional genomic, integrative biology and quanitative genetic in plants leads to a growing need of analytical chemistry. In this context, the PO-Chemistry/metabolism is dedicated to analytical and structural chemistry of molecules derived from plants. One of its strengths lies in its integration into the scientific community of the IJPB, which researches many aspects of plant physiology and functional genomics. This enables close collaboration with biology teams at local, national and international level. In addition, positioning at the interface between chemistry and biology is a strong priority and a core mission of the OV-Chemistry/Metabolism, which is already actively pursued through participation in numerous collaborative projects.
The activities and expertise of the platform are organized according to three main axes of development and service:
1. Metabolic profiling/analytical chemistry: analysis of primary and specialized plant metabolites by untargeted metabolomics, quantification and identification of lipids and lipidomics by GC-MS, UPLC-MS/MS and LC-HRMS.
2. Biochemical analysis of cell wall polymers by GC-MS, LC-HRMS, HPAEC-PAD.
3. Signalisation and plant hormones.
Models, tools and methods
The OV-Chemistry/Metabolism is housed in ~400 m2 of laboratories in Building 1 on the Versailles campus. The platform works with all plant species and plant products. The analytical methods used on the platform are primarily based on mass spectrometry with different coupling.
Societal and economical impacts
The analyses conducted by the PO-Chemistry-Metabolism supports the implementation of new agricultural practices: reduction in the use of pesticides and inputs while maintaining the quality of agricultural products and yields. The PO-Chemistry/Metabolism belongs to the SMaCS consortium which unites the mass spectrometry platforms of Université Paris-Saclay that are dedicated to the analysis of small molecules. It is also part of the network of plant metabolomic platforms of the INRAE BAP division, in the second circle of the METABOHUB ISC infrastructure.
The PO-Chemistry/Metabolism is also involved in the credit units of 4 Université Paris-Saclay Masters in Biology programmes, training 30 to 40 students per year in metabolomics through practical work and tutorials, in sessions of 3 to 5 days. Additionally, three times a year, in 'Des plantes et des Hommes' sessions, members of the platform welcome high school classes to present their activities and their job by a platform tour and an open discussion about the profession of research
The development of functional genomic, integrative biology and quanitative genetic in plants leads to a growing need of analytical chemistry. In this context, the PO-Chemistry/metabolism is dedicated to analytical and structural chemistry of molecules derived from plants. One of its strengths lies in its integration into the scientific community of the IJPB, which researches many aspects of plant physiology and functional genomics. This enables close collaboration with biology teams at local, national and international level. In addition, positioning at the interface between chemistry and biology is a strong priority and a core mission of the OV-Chemistry/Metabolism, which is already actively pursued through participation in numerous collaborative projects.
The activities and expertise of the platform are organized according to three main axes of development and service:
1. Metabolic profiling/analytical chemistry: analysis of primary and specialized plant metabolites by untargeted metabolomics, quantification and identification of lipids and lipidomics by GC-MS, UPLC-MS/MS and LC-HRMS.
2. Biochemical analysis of cell wall polymers by GC-MS, LC-HRMS, HPAEC-PAD.
3. Signalisation and plant hormones.
Models, tools and methods
The OV-Chemistry/Metabolism is housed in ~400 m2 of laboratories in Building 1 on the Versailles campus. The platform works with all plant species and plant products. The analytical methods used on the platform are primarily based on mass spectrometry with different coupling.
Societal and economical impacts
The analyses conducted by the PO-Chemistry-Metabolism supports the implementation of new agricultural practices: reduction in the use of pesticides and inputs while maintaining the quality of agricultural products and yields. The PO-Chemistry/Metabolism belongs to the SMaCS consortium which unites the mass spectrometry platforms of Université Paris-Saclay that are dedicated to the analysis of small molecules. It is also part of the network of plant metabolomic platforms of the INRAE BAP division, in the second circle of the METABOHUB ISC infrastructure.
The PO-Chemistry/Metabolism is also involved in the credit units of 4 Université Paris-Saclay Masters in Biology programmes, training 30 to 40 students per year in metabolomics through practical work and tutorials, in sessions of 3 to 5 days. Additionally, three times a year, in 'Des plantes et des Hommes' sessions, members of the platform welcome high school classes to present their activities and their job by a platform tour and an open discussion about the profession of research
PHOTOS
