Biologie des Génomes

Füssy Z, Hampe RH, Arrigo KR, Barry K, Brisbin MM, Brussaard CPD, Decelle J, de Vargas C, DiTullio GR, Elbourne LDH, Frischer ME, Goodstein DM, Grigoriev IV, Hayes RD, Healey AL, James CC, Jenkins JW, Juery C, Kumar M, Kustka AB, Maumus F, et al. (2025). Genome-resolved biogeography of Phaeocystales, cosmopolitan bloom-forming algae. Nat Commun, 16(1):8559. PubMed | DOI

Baduel P, De Oliveira L, Caillieux E, Bohl-Viallefond G, Xu C, El Messaoudi M, Petit A, Draï M, Barrois M, Singh V, Sarazin A, Teixeira FK, Boccara M, Gilbault E, de France A, Quadrana L, Loudet O, Colot V (2025). Transposable elements are vectors of recurrent transgenerational epigenetic inheritance. Science, eady3475. PubMed | DOI

Chanteau A, Quilleré S, Crouset A, Allipra S, Tuquoi U, Perroud PF, Miron S, Dupaigne P, Zinn-Justin S, Nogué F, Kumar R (2025). Moss BRCA2 lacking the canonical DNA-binding domain promotes homologous recombination and binds to DNA. Nucleic Acids Res, 53(17):gkaf856. PubMed | DOI

Wang Ch, Quadrado M, Ngom T, Mireau H (2025). Plant mitochondrial PORR proteins facilitate group II intron splicing by binding to distinct regions within their target introns. Nucleic Acids Res, 53(15):gkaf781. PubMed | DOI

Sakamoto AN, Yokota Y, Perroud PF, Oshima Y, Nogué F, Hase Y (2025). The model moss Physcomitrium patens relies heavily on homologous recombination to repair DNA double-strand breaks. DNA Repair (Amst), 152:103881. PubMed | DOI

Cai B, Tiscareño Andrade M, Luo Y, Lefranc S, Cao F, Chambon A, Yuan X, Peuch M, Zhang Ya, Hurel A, Guérin J, Vrielynck N, Mézard C, Andrey P, Cromer L, Yang C, Grelon M (2025). Identification of the cytoplasmic motor-LINC complex involved in rapid chromosome movements during meiotic prophase in Arabidopsis thaliana. Nat Plants,11(8):1608-1627. PubMed | DOI

Martinez Rivas FJ, Wozny D, Xue Z, Gilbault E, Sapir T, Rouillé M, Ricou A, Medina J, Noël LD, Lauber E, Voxeur A, Mazier M, Loudet O, Clément G, Jiménez-Gómez JM (2025). Parallel evolution of salinity tolerance in Arabidopsis thaliana accessions from Cape Verde Islands. Sci Adv 11(28):eadq8210. PubMed | DOI

Lécureuil A, Corso M, Boutet S, Le Gall S, Niñoles R, Gadea J, Guerche P, Jasinski S (2025). Innovative screening for mutants affected in seed oil/protein allocation identifies TRANSPARENT TESTA7 as a regulator of oil accumulation. Plant J, 122(6):e70269. PubMed | DOI

Soulard C, Monfort M, Pillot JP, Géry C, Chauvin L, Morlière S, Lesné A, Sugio A, Pilet-Nayel ML, Rameau C, Nogué F, De Saint Germain A (2025). Efficient and heritable gene editing through CRISPR-Cas9 in Pisum sativum. Plant Biotechnol J, https://doi.org/10.1111/pbi.70091. PubMed | DOI

Takatsuka A, Iwai Y, Mireau H, Kazama T, Ichida H, Abe T, Igarashi K, Toriyama K (2025). A Pentatricopeptide Repeat Protein Restores Fertility in Tadukan-Type Cytoplasmic Male Sterile Rice via the Cleavage of the Mitochondrial orf312 RNA. Physiol Plant, 177(3):e70308. PubMed | DOI

Emmenecker C, Dai J, Lefranc S, Ouddah A, Guérin J, Pakzad S, Andrey P, Kumar R (2025). A high-throughput differential chemical genetic screen uncovers genotype-specific compounds altering plant growth. iScience, 28(5):112375. PubMed | DOI

Elmayan T, Blein T, Elvira Matelot E, Le Masson I, Christ A, Bouteiller N, Crespi MD, Vaucheret H (2025). Arabidopsis SGS3 is recruited to chromatin by CHR11 to select RNA that initiate siRNA production. Nat Commun, 16(1):2978. PubMed | DOI

Boussardon C, Simon M, Carrie C, Fuszard M, Meyer EH, Budar F, Keech O (2025). The atypical proteome of mitochondria from mature pollen grains. Curr Biol, 35(4):776-787. PubMed | DOI

Kumar R (2025). FIGNL1 hexamer dissociates RAD51-filament: a new mechanism. Trends Biochem Sci, S0968-0004(25)00002-7. PubMed | DOI

Ricou A, Simon M, Duflos R, Azzopardi M, Roux F, Budar F, Camilleri C (2025). Identification of novel genes responsible for a pollen killer present in local natural populations of Arabidopsis thaliana. PLoS Genet, 21(1):e1011451. PubMed | DOI

Emmenecker C, Pakzad S, Ture F, Guérin J, Hurel A, Chambon A, Girard C, Mercier R, Kumar R (2024). FIGL1 attenuates meiotic interhomolog repair and is counteracted by the RAD51 paralog XRCC2 and the chromosome axis protein ASY1 during meiosis. New Phytol, doi: 10.1111/nph.20181. PubMed | DOI

Dehaene N, Boussardon C, Andrey P, Charif D, Brandt D, Gilouppe Taillefer C, Nietzel T, Ricou A, Simon M, Tran J, Vezon D, Camilleri C, Arimura SI, Schwarzländer M, Budar F (2024). The mitochondrial orf117Sha gene desynchronizes pollen development and causes pollen abortion in Arabidopsis Sha cytoplasmic male sterility. J Exp Bot, 75(16):4851-4872. PubMed | DOI

Tavernier EK, Perroud PF, Lockwood E, Nogué F, McDaniel SF (2024). Establishing CRISPR-Cas9 in the sexually dimorphic moss, Ceratodon purpureus. Plant J, doi: 10.1111/tpj.16946. PubMed | DOI

Zainu A, Dupaigne P, Bouchouika S, Cau J, Clément JAJ, Auffret P, Ropars V, Charbonnier JB, De Massy B, Mercier R, Kumar R, Baudat F (2024). FIGNL1-FIRRM is essential for meiotic recombination and prevents DNA damage-independent RAD51 and DMC1 loading. Nat Commun, 15(1):7015. PubMed | DOI

Cromer L, Tiscareño Andrade M, Lefranc S, Chambon A, Hurel A, Brogniez M, Guérin J, Le Masson I, Adam G, Charif D, Andrey P, Grelon M (2024). Rapid meiotic prophase chromosome movements in Arabidopsis thaliana are linked to essential reorganization at the nuclear envelope. Nat Commun, 15(1):5964. PubMed | DOI

Capilla-Pérez L, Solier V, Gilbault E, Lian Q, Goel M, Huettel B, Keurentjes JJ, Loudet O, Mercier R (2024). Enhanced recombination empowers the detection and mapping of Quantitative Trait Loci. Commun Biol, 7(1):829. PubMed | DOI

Xue Z, Ferrand M, Gilbault E, Zurfluh O, Clément G, Marmagne A, Huguet S, Jiménez-Gómez JM, Krapp A, Meyer C, Loudet O (2024). Natural variation in response to combined water and nitrogen deficiencies in Arabidopsis. Plant Cell, koae173. PubMed | DOI

Pachamuthu K, Simon M, Borges F (2024). Targeted suppression of siRNA biogenesis in Arabidopsis pollen promotes triploid seed viability. Nat Commun, 15(1):4612. PubMed | DOI

Calbry J, Goudounet G, Charlot F, Guyon-Debast A, Perroud PF, Nogué F (2024). The SpRY Cas9 variant release the PAM sequence constraint for genome editing in the model plant Physcomitrium patens. Transgenic Res, 33(1-2):67-74. PubMed | DOI

Goelzer A, Rajjou L, Chardon F, Loudet O, Fromion V (2024). Resource allocation modeling for autonomous prediction of plant cell phenotypes. Metab Eng, 83:86-101. PubMed | DOI

Chen HW, Yeh HY, Chang CC, Kuo WC, Lin SW, Vrielynck N, Grelon M, Chan NL, Chi P (2024). Biochemical characterization of the meiosis-essential yet evolutionarily divergent topoisomerase VIB-like protein MTOPVIB from Arabidopsis thaliana. Nucleic Acids Res, gkae181. PubMed | DOI

Kim H, Kim J, Son N, Kuo P, Morgan C, Chambon A, Byun D, Park J, Lee Y, Park YM, Fozard JA, Guérin J, Hurel A, Lambing C, Howard M, Hwang I, Mercier R, Grelon M, Henderson IR, Choi K (2024). Control of meiotic crossover interference by a proteolytic chaperone network. Nat Plants, doi: 10.1038/s41477-024-01633-y. PubMed | DOI

Wang C, Quadrado M, Mireau H (2024). Temperature-sensitive splicing defects in Arabidopsis mitochondria caused by mutations in the ROOT PRIMORDIUM DEFECTIVE 1 gene. Nucleic Acids Res, gkae072. PubMed | DOI

Nogué F, Causse M, Debaeke P, Déjardin A, Lemarié S, Richard G, Rogowsky PM, Caranta C (2024). Can genome editing help transitioning to agroecology ?. iScience, 27(3):109159. PubMed | DOI

Blagojevic A, Baldrich P, Schiaffini M, Lechner E, Baumberger N, Hammann P, Elmayan T, Garcia D, Vaucheret H, Meyers BC, Genschik P (2024). Heat stress promotes Arabidopsis AGO1 phase separation and association with stress granule components. iScience, 27(3):109151. PubMed | DOI

Djennane S, Gersch S, Le-Bohec F, Piron MC, Baltenweck R, Lemaire O, Merdinoglu D, Hugueney P, Nogué F, Mestre P (2023). Reduced susceptibility to downy mildew in grapevine plants edited for VvDMR6-1. J Exp Bot, erad487. PubMed | DOI

Vrielynck N, Peuch M, Durand S, Lian Q, Chambon A, Hurel A, Guérin J, Guerois R, Mercier R, Grelon M, Mézard C (2023). SCEP1 and SCEP2 are two new components of the synaptonemal complex central element. Nat Plants, doi: 10.1038/s41477-023-01558-y. PubMed | DOI

Shahzad Z, Tournaire-Roux C, Canut M, Adamo M, Roeder J, Verdoucq L, Martiniere A, Amtmann A, Santoni V, Grill E, Loudet O, Maurel C (2023). Protein kinase SnRK2.4 is a key regulator of aquaporins and root hydraulics in Arabidopsis. Plant J, 117: 264-279. PubMed | DOI

Vaucheret H, Voinnet O (2023). The plant siRNA landscape. Plant Cell, koad253. PubMed | DOI

Tran HC, Schmitt V, Lama S, Wang C, Launay-Avon A, Bernfur K, Sultan K, Khan K, Brunaud V, Liehrmann A, Castandet B, Levander F, Rasmusson AG, Mireau H, Delannoy E, van Aken O (2023). An mTRAN-mRNA interaction mediates mitochondrial translation initiation in plants. Science, 381(6661):eadg0995. PubMed | DOI

Pachamuthu K, Borges F (2023). Epigenetic control of transposons during plant reproduction: From meiosis to hybrid seeds. Curr Opin Plant Biol, 75:102419. PubMed | DOI

Wang C, Quadrado M, Mireau H (2023). Interplay of endonucleolytic and exonucleolytic processing in the 3'-end formation of a mitochondrial nad2 RNA precursor in Arabidopsis. Nucleic Acids Res, gkad493. PubMed | DOI

Singh DK, Lian Q, Durand S, Fernandes J, Chambon A, Hurel A, Walkemeier B, Solier V, Kumar R, Mercier R (2023). HEIP1 is required for efficient meiotic crossover implementation and is conserved from plants to humans. Proc Natl Acad Sci, 120(23):e2221746120. PubMed | DOI

Perroud PF, Guyon-Debast A, Casacuberta JM, Paul W, Pichon JP, Comeau D, Nogué F (2023). Improved Prime Editing allows for routine predictable gene editing in Physcomitrium patens. J Exp Bot, erad189. PubMed | DOI

Bazin J, Elvira Matelot E, Blein T, Jauvion V, Bouteiller N, Cao J, Crespi M, Vaucheret H (2023). Synergistic action of the Arabidopsis spliceosome components PRP39a and SmD1b in promoting post-transcriptional transgene silencing. Plant Cell, koad091. PubMed | DOI

Garcias-Morales D, Palomar VM, Charlot F, Nogué F, Covarrubias AA, Reyes JL (2023). N6 -Methyladenosine modification of mRNA contributes to the transition from 2D to 3D growth in the moss Physcomitrium patens. Plant J, doi: 10.1111/tpj.16149. PubMed | DOI

Vaucheret H (2023). Epigenetic management of self and non-self: lessons from 40 years of transgenic plants. C R Biol, 345(4):149-174. PubMed | DOI

Elfarargi AF, Gilbault E, Döring N, Neto C, Fulgione A, Weber APM, Loudet O, Hancock AM (2023). Genomic basis of adaptation to a novel precipitation regime. Mol Biol Evol, msad031. PubMed | DOI

Kuroiwa K, Danilo B, Perrot L, Thenault C, Veillet F, Delacote F, Duchateau F, Nogué F, Mazier M, Gallois JL (2023). An iterative gene-editing strategy broadens eIF4E1 genetic diversity in Solanum lycopersicum and generates resistance to multiple potyvirus isolates. Plant Biotechnol J, doi: 10.1111/pbi.14003. PubMed | DOI

Sehki H, Yu A, Elmayan T, Vaucheret H (2023). TYMV and TRV infect Arabidopsis thaliana by expressing weak suppressors of RNA silencing and inducing host RNASE THREE LIKE1. PLoS Pathog, 19(1):e1010482. PubMed | DOI

Beraldo C, Guyon-Debast A, Alboresi A, Nogué F, Morosinotto T (2023). Functional analysis of PsbS transmembrane domains through base editing in Physcomitrium patens. Plant J, doi: 10.1111/tpj.16099. PubMed | DOI

Durand S, Lian Q, Jing J, Ernst M, Grelon M, Zwicker D, Mercier R (2022). Joint control of meiotic crossover patterning by the synaptonemal complex and HEI10 dosage. Nat Commun, 13(1):5999. PubMed | DOI

Bellec Y, Guyon-Debast A, Francois T, Gissot L, Biot E, Nogué F, Faure JD, Tepfer M (2022). New Flowering and Architecture Traits Mediated by Multiplex CRISPR-Cas9 Gene Editing in Hexaploid Camelina sativa. Agronomy, 12(8): 1873. DOI

Bessoltane N, Charlot F, Guyon-Debast A, Charif D, Mara K, Collonnier C, Perroud PF, Tepfer M, Nogué F (2022). Genome-wide specificity of plant genome editing by both CRISPR-Cas9 and TALEN. Sci Rep, 12(1):9330. PubMed | DOI

Charlot F, Goudounet G, Nogué F, Perroud PF (2022). Physcomitrium patens Protoplasting and Protoplast Transfection. Methods Mol Biol, 2464:3-19. PubMed | DOI